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The lack of standardized methods to evaluate total antioxidant capacity and the oxidation state and the use of inadequate antioxidants and/or improper concentrations of antioxidants lead to failure of numerous clinical trials directed to prevent or mitigate progression of atherosclerosis (230233)

And so do the stories from people who have tried is

Painkillers can temporarily dull the pain, and surgery often comes with long recovery times

doi: 10.1016/j.semcancer.2024.09.005 85 BradfordHFMcDonnellTCRStewartASkeltonANgJBaigZet al

We believe that this concept could be extended to develop improved fluorescent sensors for other analytes